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1

Dynamic asymmetric organocatalysis: cooperative effects of weak interactions and conformational flexibility in asymmetric organocatalysts

Sohtome, Yoshihiro, Nagasawa, Kazuo

Journal:

Chemical Communications

Year:

2012

Language:

english

File:

PDF, 1.75 MB

english, 2012

2

Brønsted Base and Acid Catalysts, and Additional Topics || Hydrogen-Bonding Catalysts: (Thio)urea Catalysis

Nagasawa, K., Sohtome, Y., Singh, R. P., Deng, L., Jang, H. B., Oh, J. S., Song, C. E., Akiyama, T., Terada, M., Momiyama, N., Hashimoto, T., Hof, K., Lippert, K. M., Schreiner, P. R., Uraguchi, D., O

Year:

2012

Language:

english

File:

PDF, 1.29 MB

english, 2012

3

Multiselective Catalytic Asymmetric Reactions Using α-Keto Esters as Pronucleophiles

Sohtome, Yoshihiro, Sodeoka, Mikiko

Journal:

Year:

2019

File:

PDF, 1.04 MB

2019

4

Guanidine-Thiourea Bifunctional Organocatalyst for the Asymmetric Henry (Nitroaldol) Reaction

Yoshihiro Sohtome, Yuichi Hashimoto, Kazuo Nagasawa

Journal:

Advanced Synthesis & Catalysis

Year:

2005

Language:

english

File:

PDF, 112 KB

english, 2005

5

Enantioselective Phospha-Michael Reaction of Diphenyl Phosphonate with Nitroolefins Utilizing Conformationally Flexible Guanidinium/Bisthiourea Organocatalyst: Assembly-State Tunability in Asymmetric Organocatalysis

Yoshihiro Sohtome, Natsuko Horitsugi, Rika Takagi, Kazuo Nagasawa

Journal:

Advanced Synthesis & Catalysis

Year:

2011

Language:

english

File:

PDF, 230 KB

english, 2011

6

A Heterobimetallic Pd/La/Schiff Base Complex for anti-Selective Catalytic Asymmetric Nitroaldol Reactions and Applications to Short Syntheses of β-Adrenoceptor Agonists

Shinya Handa, Keita Nagawa, Yoshihiro Sohtome, Shigeki Matsunaga, Masakatsu Shibasaki

Journal:

Angewandte Chemie

Year:

2008

Language:

english

File:

PDF, 349 KB

english, 2008

7

Entropy-Controlled Catalytic Asymmetric 1,4-Type Friedel–Crafts Reaction of Phenols Using Conformationally Flexible Guanidine/Bisthiourea Organocatalyst

Dr. Yoshihiro Sohtome, Bongki Shin, Natsuko Horitsugi, Rika Takagi, Prof. Dr. Keiichi Noguchi, Prof. Dr. Kazuo Nagasawa

Journal:

Angewandte Chemie

Year:

2010

Language:

english

File:

PDF, 355 KB

english, 2010

8

Solvent-Dependent Enantiodivergent Mannich-Type Reaction: Utilizing a Conformationally Flexible Guanidine/Bisthiourea Organocatalyst

Dr. Yoshihiro Sohtome, Shinji Tanaka, Keisuke Takada, Takahisa Yamaguchi, Prof. Dr. Kazuo Nagasawa

Journal:

Angewandte Chemie

Year:

2010

Language:

english

File:

PDF, 350 KB

english, 2010

9

A Heterobimetallic Pd/La/Schiff Base Complex for anti-Selective Catalytic Asymmetric Nitroaldol Reactions and Applications to Short Syntheses of β-Adrenoceptor Agonists

Shinya Handa, Keita Nagawa, Yoshihiro Sohtome, Shigeki Matsunaga, Masakatsu Shibasaki

Journal:

Angewandte Chemie International Edition

Year:

2008

Language:

english

File:

PDF, 349 KB

english, 2008

10

Entropy-Controlled Catalytic Asymmetric 1,4-Type Friedel–Crafts Reaction of Phenols Using Conformationally Flexible Guanidine/Bisthiourea Organocatalyst

Dr. Yoshihiro Sohtome, Bongki Shin, Natsuko Horitsugi, Rika Takagi, Prof. Dr. Keiichi Noguchi, Prof. Dr. Kazuo Nagasawa

Journal:

Angewandte Chemie International Edition

Year:

2010

Language:

english

File:

PDF, 391 KB

english, 2010

11

Solvent-Dependent Enantiodivergent Mannich-Type Reaction: Utilizing a Conformationally Flexible Guanidine/Bisthiourea Organocatalyst

Dr. Yoshihiro Sohtome, Shinji Tanaka, Keisuke Takada, Takahisa Yamaguchi, Prof. Dr. Kazuo Nagasawa

Journal:

Angewandte Chemie International Edition

Year:

2010

Language:

english

File:

PDF, 369 KB

english, 2010

12

Development of Novel Chiral Urea Catalysts for the Hetero-Michael Reaction.

Yoshihiro Sohtome, Aya Tanatani, Yuichi Hashimoto, Kazuo Nagasawa

Journal:

Year:

2004

File:

PDF, 89 KB

2004

13

Development of Bis-thiourea-Type Organocatalyst for Asymmetric Baylis—Hillman Reaction.

Yoshihiro Sohtome, Aya Tanatani, Yuichi Hashimoto, Kazuo Nagasawa

Journal:

Year:

2004

File:

PDF, 16 KB

2004

14

ChemInform Abstract: The Design of Chiral Double Hydrogen Bonding Networks and Their Applications to Catalytic Asymmetric Carbon—Carbon and Carbon—Oxygen Bond-Forming Reactions

Yoshihiro Sohtome, Kazuo Nagasawa

Journal:

Year:

2010

File:

PDF, 16 KB

2010

15

ChemInform Abstract: Entropy-Controlled Catalytic Asymmetric 1,4-Type Friedel—Crafts Reaction of Phenols Using Conformationally Flexible Guanidine/Bisthiourea Organocatalyst.

Yoshihiro Sohtome, Bongki Shin, Natsuko Horitsugi, Rika Takagi, Keiichi Noguchi, Kazuo Nagasawa

Journal:

Year:

2011

File:

PDF, 49 KB

2011

16

ChemInform Abstract: Solvent-Dependent Enantiodivergent Mannich-Type Reaction: Utilizing a Conformationally Flexible Guanidine/Bisthiourea Organocatalyst.

Yoshihiro Sohtome, Shinji Tanaka, Keisuke Takada, Takahisa Yamaguchi, Kazuo Nagasawa

Journal:

Year:

2011

File:

PDF, 32 KB

2011

17

ChemInform Abstract: Organocatalytic Asymmetric Synthesis of N,N-Bis(dihydrofuranyl)hydroxyamines: A Cascade Reaction Involving Friedel—Crafts Alkylation, Internal Redox Reaction, and Umpolung.

Yoshihiro Sohtome, Takahisa Yamaguchi, Bongki Shin, Kazuo Nagasawa

Journal:

Year:

2012

File:

PDF, 41 KB

2012

18

ChemInform Abstract: Dynamic Enantiodivergent Organocatalysis: Merging Molecular Motors with Bifunctional Organocatalysts

Yoshihiro Sohtome, Kazuo Nagasawa

Journal:

Year:

2012

File:

PDF, 18 KB

2012

19

ChemInform Abstract: Enantioselective Phospha-Michael Reaction of Diphenyl Phosphonate with Nitroolefins Utilizing Conformationally Flexible Guanidinium/Bisthiourea Organocatalyst: Assembly-State Tunability in Asymmetric Organocatalysis.

Yoshihiro Sohtome, Natsuko Horitsugi, Rika Takagi, Kazuo Nagasawa

Journal:

Year:

2012

File:

PDF, 44 KB

2012

20

Dynamic Enantiodivergent Organocatalysis: Merging Molecular Motors with Bifunctional Organocatalysts

Dr. Yoshihiro Sohtome, Prof. Dr. Kazuo Nagasawa

Journal:

Year:

2011

Language:

english

File:

PDF, 262 KB

english, 2011

21

Diastereoselective and Enantioselective Henry (Nitroaldol) Reaction Utilizing a Guanidine-Thiourea Bifunctional Organocatalyst

Yoshihiro Sohtome, Yuichi Hashimoto, Kazuo Nagasawa

Journal:

European Journal of Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 112 KB

english, 2006

22

A method for the synthesis of an oseltamivir PET tracer

Masataka Morita, Toshihiko Sone, Kenzo Yamatsugu, Yoshihiro Sohtome, Shigeki Matsunaga, Motomu Kanai, Yasuyoshi Watanabe, Masakatsu Shibasaki

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 120 KB

english, 2008

23

Thiourea-catalyzed Morita–Baylis–Hillman reaction

Yoshihiro Sohtome, Nobuko Takemura, Rika Takagi, Yuichi Hashimoto, Kazuo Nagasawa

Journal:

Year:

2008

Language:

english

File:

PDF, 616 KB

english, 2008

24

Development of bis-thiourea-type organocatalyst for asymmetric Baylis–Hillman reaction

Yoshihiro Sohtome, Aya Tanatani, Yuichi Hashimoto, Kazuo Nagasawa

Journal:

Tetrahedron Letters

Year:

2004

Language:

english

File:

PDF, 272 KB

english, 2004

25

Asymmetric organocatalytic nitroaldol reaction of α-ketoesters: stereoselective construction of chiral tertiary alcohols at subzero temperature

Keisuke Takada, Nobuko Takemura, Kaori Cho, Yoshihiro Sohtome, Kazuo Nagasawa

Journal:

Tetrahedron Letters

Year:

2008

Language:

english

File:

PDF, 155 KB

english, 2008

26

Potassium 2,3,4-trihydroxy-2-methylbutanoate, a leaf-closing substance of Leucaena leucocephalam

Minoru Ueda, Yoshihiro Sohtome, Katsuhiro Ueda, Shosuke Yamamura

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 56 KB

english, 2001

27

Offshore collection of larval Japanese flounderParalichthys olivaceus: implication for transport-induced mortality

Takeshi TOMIYAMA, Takuji MIZUNO, Daisuke UENOYAMA, Masahiro ENOMOTO, Tadahiro SOHTOME

Journal:

Fisheries Science

Year:

2008

Language:

english

File:

PDF, 200 KB

english, 2008

28

Organocatalytic Asymmetric Nitroaldol Reaction: Cooperative Effects of Guanidine and Thiourea Functional Groups

Yoshihiro Sohtome, Nobuko Takemura, Keisuke Takada, Rika Takagi, Toshitsugu Iguchi, Kazuo Nagasawa

Journal:

Chemistry – An Asian Journal

Year:

2007

Language:

english

File:

PDF, 225 KB

english, 2007

29

Chiral-Catalyst-Based Convergent Synthesis of HIV Protease Inhibitor GRL-06579A

Hisashi Mihara, Yoshihiro Sohtome, Shigeki Matsunaga, Masakatsu Shibasaki

Journal:

Chemistry – An Asian Journal

Year:

2008

Language:

english

File:

PDF, 295 KB

english, 2008

30

Linking Conformational Flexibility and Kinetics: Catalytic 1,4-Type Friedel–Crafts Reactions of Phenols Utilizing 1,3-Diamine-Tethered Guanidine/Bisthiourea Organocatalysts

Dr. Yoshihiro Sohtome, Bongki Shin, Natsuko Horitsugi, Prof. Dr. Keiichi Noguchi, Prof. Dr. Kazuo Nagasawa

Journal:

Chemistry – An Asian Journal

Year:

2011

Language:

english

File:

PDF, 608 KB

english, 2011

31

Stereodivergent Catalytic Doubly Diastereoselective Nitroaldol Reactions Using Heterobimetallic Complexes

Sohtome, Yoshihiro, Kato, Yuko, Handa, Shinya, Aoyama, Naohiro, Nagawa, Keita, Matsunaga, Shigeki, Shibasaki, Masakatsu

Journal:

Organic Letters

Year:

2008

Language:

english

File:

PDF, 205 KB

english, 2008

32

ChemInform Abstract: Dynamic Asymmetric Organocatalysis: Cooperative Effects of Weak Interactions and Conformational Flexibility in Asymmetric Organocatalysts

Yoshihiro Sohtome, Kazuo Nagasawa

Journal:

Year:

2012

File:

PDF, 18 KB

2012

33

Sequential enantiodivergent organocatalysis: reversibility in enantioswitching controlled by a conformationally flexible guanidine/bisthiourea organocatalyst

Sohtome, Yoshihiro, Yamaguchi, Takahisa, Tanaka, Shinji, Nagasawa, Kazuo

Journal:

Organic & Biomolecular Chemistry

Year:

2013

Language:

english

File:

PDF, 358 KB

english, 2013

34

Epidithiodiketopiperazine as a pharmacophore for protein lysine methyltransferase G9a inhibitors: Reducing cytotoxicity by structural simplification

Fujishiro, Shinya, Dodo, Kosuke, Iwasa, Eriko, Teng, Yuou, Sohtome, Yoshihiro, Hamashima, Yoshitaka, Ito, Akihiro, Yoshida, Minoru, Sodeoka, Mikiko

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.04 MB

english, 2013

35

Molecular cloning, characterization and analysis of the intracellular localization of a water-soluble chlorophyll-binding protein (WSCP) from Virginia pepperweed (Lepidium virginicum), a unique WSCP that preferentially binds chlorophyllbin vitro

Takahashi, Shigekazu, Yanai, Haruna, Oka-Takayama, Yuko, Zanma-Sohtome, Aya, Fujiyama, Kosaku, Uchida, Akira, Nakayama, Katsumi, Satoh, Hiroyuki

Journal:

Year:

2013

Language:

english

File:

PDF, 1.24 MB

english, 2013

36

Sequential stereodivergent organocatalysis and programmed organocascades

Sohtome, Yoshihiro, Nagasawa, Kazuo

Journal:

Organic & Biomolecular Chemistry

Year:

2014

Language:

english

File:

PDF, 1.53 MB

english, 2014

37

Effects of the nuclear disaster on marine products in Fukushima

Wada, Toshihiro, Nemoto, Yoshiharu, Shimamura, Shinya, Fujita, Tsuneo, Mizuno, Takuji, Sohtome, Tadahiro, Kamiyama, Kyoichi, Morita, Takami, Igarashi, Satoshi

Journal:

Journal of Environmental Radioactivity

Year:

2013

Language:

english

File:

PDF, 2.04 MB

english, 2013

38

Asymmetric Michael Reaction of Nitroolefins with β-Dicarbonyl Compounds Catalysed by 1,3-Diamine-Tethered Guanidine-Thiourea Bifunctional Organocatalysts

Horitsugi, Natsuko, Kojima, Kohei, Yasui, Koji, Sohtome, Yoshihiro, Nagasawa, Kazuo

Journal:

Asian Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 246 KB

english, 2014

39

A concise quantum efficiency measurement system for gaseous photomultipliers

Moriya, Toru, Tokanai, Fuyuki, Okazaki, Keisuke, Sakurai, Hirohisa, Gunji, Shuichi, Kawabata, Hironobu, Sohtome, Takayuki, Sumiyoshi, Takayuki, Sugiyama, Hirioyuki, Okada, Teruyuki, Ohishi, Noboru, Ki

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

2013

Language:

english

File:

PDF, 574 KB

english, 2013

40

The Design of Chiral Double Hydrogen Bonding Networks and Their Applications to Catalytic Asymmetric Carbon-Carbon and Carbon-Oxygen Bond-Forming Reactions

Sohtome, Yoshihiro, Nagasawa, Kazuo

Journal:

Year:

2010

Language:

english

File:

PDF, 460 KB

english, 2010

41

Catalytic Asymmetric Cyclopropanation of Enones with Dimethyloxosulfonium Methylide Promoted by a La−Li 3 −(Biphenyldiolate) 3 + NaI Complex

Kakei, Hiroyuki, Sone, Toshihiko, Sohtome, Yoshihiro, Matsunaga, Shigeki, Shibasaki, Masakatsu

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 51 KB

english, 2007

42

Aromatase Reaction of 3-Deoxyandrogens: Steric Mode of the C-19 Oxygenation and Cleavage of the C 10 −C 19 Bond by Human Placental Aromatase †

Numazawa, Mitsuteru, Nagaoka, Masao, Sohtome, Norishige

Journal:

Year:

2005

Language:

english

File:

PDF, 119 KB

english, 2005

43

Radiological impact of TEPCO's Fukushima Dai-ichi Nuclear Power Plant accident on invertebrates in the coastal benthic food web

Sohtome, Tadahiro, Wada, Toshihiro, Mizuno, Takuji, Nemoto, Yoshiharu, Igarashi, Satoshi, Nishimune, Atsushi, Aono, Tatsuo, Ito, Yukari, Kanda, Jota, Ishimaru, Takashi

Journal:

Journal of Environmental Radioactivity

Year:

2014

Language:

english

File:

PDF, 1.17 MB

english, 2014

44

High temperature crack sealant based on SiO2-B2O3 for SiC coating on carbon–carbon composites

Hatta, Hiroshi, Sohtome, Takayuki, Sawada, Yutaka, Shida, Azusa

Journal:

Advanced Composite Materials

Year:

2003

Language:

english

File:

PDF, 724 KB

english, 2003

45

Leaf-closing Substance in Leucaena leucocephala

SOHTOME, Yoshihiro, TOKUNAGA, Takashi, UEDA, Katsuhiro, YAMAMURA, Shosuke, UEDA, Minoru

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2002

Language:

english

File:

PDF, 227 KB

english, 2002

46

A Hepatocellular Carcinoma of Massive Arterioportal Shunts Without Tumor Stain Treated with CDDP Two-Route Chemotherapy A Case Report

Matama, S., Ishii, K., Satoh, K., Sohtome, S., Sasaki, K.

Journal:

Year:

1990

Language:

english

File:

PDF, 392 KB

english, 1990

47

Corrigendum to “Effects of the nuclear disaster on marine products in Fukushima”

Wada, Toshihiro, Nemoto, Yoshiharu, Shimamura, Shinya, Fujita, Tsuneo, Mizuno, Takuji, Sohtome, Tadahiro, Kamiyama, Kyoichi, Morita, Takami, Igarashi, Satoshi

Journal:

Journal of Environmental Radioactivity

Year:

2014

Language:

english

File:

PDF, 138 KB

english, 2014

48

Design and Synthesis of Telomestatin Derivatives and Their Inhibitory Activity of Telomerase

Nagasawa, Kazuo, Tera, Masayuki, Sohtome, Yoshihiro, Ishizuka, Hiromichi, Doi, Takayuki, Takagi, Motoki, Shin-ya, Kazuo

Journal:

Year:

2006

Language:

english

File:

PDF, 534 KB

english, 2006

49

Enantioswitching Catalysis with a Single Chiral Organocatalyst

Sohtome, S., Tanaka, S., Takada, K., Yamaguchi, T., Nagasawa, K.

Journal:

Year:

2011

Language:

english

File:

PDF, 72 KB

english, 2011

50

Pd/La Complex for anti -Selective Catalytic Asymmetric Nitroaldol Reactions

Handa, S., Nagawa, K., Sohtome, Y., Matsunaga, S., Shibasaki, M.

Journal:

Year:

2008

Language:

english

File:

PDF, 73 KB

english, 2008